2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
    Neuronal Signaling
  4. TRP Channel
  5. TRPM4 Isoform

TRPM4

 

TRPM4 Related Products (4):

Cat. No. Product Name Effect Purity
  • HY-128172
    TRPM4-IN-2
    		Inhibitor 99.17%
    TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibitor with an IC50 value of 0.16 μM. TRPM4-IN-2 can be used for researching prostate cancer and colorectal cancer.
  • HY-108457
    9-Phenanthrol
    		Inhibitor 99.61%
    9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC50 of 17 μM. 9-Phenanthrol has no inhibitory activity on TRPM5, TRPC6, and CFTR. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury.
  • HY-153468
    ErSO-TFPy
    		Activator 99.33%
    ErSO-TFPy (TEQ103) is an ERα+ tumor cell inhibitor with low nanomolar cytotoxic activity against ERα+ breast cancer cells. ErSO-TFPy activates the sodium channel TRPM4, causes an imbalance of intracellular calcium and sodium ions. ErSO-TFPy dysregulates calcium homeostasis in ERα+ tumor cells, triggers the anticipatory unfolded protein response, and induces rapid immune cell-independent necrotic cell death. ErSO-TFPy can be used for the research of estrogen receptor alpha positive breast cancer.
  • HY-183268
    TRPM4-IN-4
    		Inhibitor
    TRPM4-IN-4 (Compound 118) is a selective TRPM4 inhibitor with an IC50 value of 0.339 μM against hTRPM4. TRPM4-IN-4 inhibits hTRPM4 and mTRPM4. TRPM4-IN-4 can be used for the research of colorectal cancer.